Research Highlights

Journal Covers

ijc chemsocrev

Maitotoxin: An Inspiration for Synthesis, K. C. Nicolaou, R. J. Aversa, Isr. J. Chem. 2011, 51, 359–377.

The Art of Total Synthesis Through Cascade Reactions, K. C. Nicolaou, J. S. Chen, Chem. Soc. Rev. 2009, 38, 2993–3009.

angewandte joc

Total Synthesis and and Absolute Configuration of the Bisanthraquinones Antibiotic BE-43472B, K. C. Nicolaou, Yee Hwee Lim, Jochen Becker, Angew. Chem. Int. Ed. 2009, 48, 3444-3448.

Inspriations, Discoveries, and Future Perspectives in Total Synthesis, K. C. Nicolaou, J. Org. Chem. 2009, 74, 951-972.

angewandte chemmedchem

Total Synthesis and Revised Structure of Biyouyanagin A, K. C. Nicolaou, David Sarlah, David M. Shaw, Angew. Chem. Int. Ed. 2007, 46, 4587.

Molecular Design and Chemical Synthesis of a Highly Potent Epothilone, K. C. Nicolaou, B. A. Pratt, S. Arseniyadis, M. Wartmann, A. O’Brate, P. Giannakakou, Chem. Med. Chem. 2006, 1, 41-44.

angewandte angewandte

Palladium-Catalyzed Cross-Coupling Reactions in Total Synthesis, K. C. Nicolaou, P. G. Bulger, D. Sarlah, Angew. Chem. Int. Ed. 2005, 44, 4442-4489.

Structural Revision and Total Synthesis of Azaspiracid-1. Part 1: Intelligence Gathering and Tentative Proposal, K. C. Nicolaou, S. Vyskocil, T.V. Koftis, Y. M. A. Yamada, T. Ling, D. Y.-K. Chen, W. Tang, G. Petrovic, M. O. Frederick, Y. Li, M. Satake, Angew. Chem. Int. Ed. 2004, 43, 4312-4318.

chemcomm obc

Tandem Reactions, Cascade Sequences and Biomimetic Strategies in Total Synthesis, K. C. Nicolaou, T. Montagnon, and S. Snyder, Chem. Comm. 2003, 5, 551-564.

Discovery and Optimization of Non-Steroidal FXR Agonists from Natural Product-like Libraries, K. C. Nicolaou, R. M. Evans, A. J. Roecker, R. Hughes, M. Downes, and J. A. Pfefferkorn, Org. Biomol. Chem. 2003 1, 908-920.

angewandte angewandte

The CP Molecule Labyrinth: A Paradigm of How Endeavors in Total Synthesis Lead to Discoveries and Inventions in Organic Synthesis, K. C. Nicolaou and P. S. Baran, Angew. Chem. Int. Ed. 2002, 41, 2678-2720.

The Diels-Alder Reaction in Total Synthesis, K. C. Nicolaou, S. A. Snyder, T. Montagnon, G. E. Vassilikogiannakis, Angew. Chem. Int. Ed. 2002, 41, 1668-1698.

angewandte angewandte

Art and Science of Total Synthesis at the Dawn of the the Twenty-First Century, K. C. Nicolaou, D. Vourloumis, N. Winssinger, P. S. Baran, Angew. Chem. 2000, 112, 46-126.; Angew. Chem. Int. Ed. 2000, 39, 44-122.

The Chemistry, Biology and Medicine of the Glycopeptide Antibiotics, K. C. Nicolaou, C. N. C. Boddy, S. Bräse, N. Winssinger, Angew. Chem. Int. Ed. 1999, 38, 2096-2152.

chemistry angewandte

Total Synthesis of Brevetoxin A. 1. First Generation Strategy and Construction of BCD Ring System, K. C. Nicolaou, M. E. Bunnage, D. G. McGarry, S. Shi, P. K. Somers, P. A. Wallace, X.-J. Chu, K. A. Agrios, J. L. Gunzner, Z. Yang, Chem. Eur. J. 1999, 5, 599-617.

Chemical Biology of Epothilones, K. C. Nicolaou, F. Roschangar, D. Vourloumis, Angew. Chem. Int. Ed. Engl. 1998, 37, 2014-2045.

angewandte jchemed

Zaragozic Acid A/Squalestatin S1: Synthetic and Retrosynthetic Studies, Kyriacos C. Nicolaou, Eddy W. Yue, Yoshimitsu Naniwa, Francesco De Riccardis, Alan Nadin, James E. Leresche, Susan La Greca, and Zhen Yang, Angew. Chem. Int. Ed. Engl. 1994, 33, 2184-2187.

The Art and Science of Organic and Natural Products Synthesis, K. C. Nicolaou, E. J. Sorensen, N. Winssinger, J. Chem. Ed. 1998, 75, 1225-1258.

angewandte nature

Chemistry and Biology of Taxol, Kyriacos C. Nicolaou, Wei-Min Dai, and Rodney Kiplin Guy, Angew. Chem. Int. Ed. Engl. 1994, 33, 15-44.

Total Synthesis of Taxol, K.C. Nicolaou, Z. Yang, J.J. Liu, H. Ueno, P.G. Nantermet, R.K. Guy, C.F. Claiborne, J. Renaud, E.A. Couladouros, K. Paulvannan, and E. J. Sorensen, Nature 1994, 367, 630-634.

chemistry in britain angweandte

The Magic of Enediyne Chemistry, K. C. Nicolaou, Chemistry in Britain 1994, 30, 33.

Golfomycin A, a Novel Designed Molecule with DNA-Cleaving Properties and Antitumor Activity, K. C. Nicolaou, Golfo Skokotas, S. Furuya, H. Suemune, and D. Colette Nicolaou, Angew. Chem. Int. Ed. 1990, 29, 1064.



Journal Covers

Diazonamide A
Brevetoxin B
Brevetoxin A
Benzopyran Libraries
CP molecules (C&EN)
CP molecules (science)
Epothilones (C&EN)
Epothilones (science)
Epothilones (nature)
Sarcodictyins Library
Sciencewatch 1997
Sciencewatch 1998
Taxol (C&EN)
Taxol (nature)
Zaragozic Acid